2.0M
XNAS Volume
High volume today
XNAS 21 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.98 per share. | 26 Feb 2025 | 2,362 | 26,002 (0%) | 0% | 2.0 | 4,677 | Common Stock |
| Peter D. Kies | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 31,900 | 31,900 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 39,050 | 39,050 | - | - | Common Stock Option | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 5,010 | 10,019 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 3,997 | 0 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.98 per share. | 26 Feb 2025 | 2,960 | 28,052 (0%) | 0% | 2.0 | 5,861 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 5,010 | 31,012 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 3,997 | 28,364 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 972 | 84,453 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 972 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 972 | 972 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 972 | 83,481 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 3,855 | 28,192 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.98 per share. | 26 Feb 2025 | 1,584 | 26,608 (0%) | 0% | 2.0 | 3,136 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 5,010 | 31,618 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.98 per share. | 26 Feb 2025 | 2,059 | 29,559 (0%) | 0% | 2.0 | 4,077 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 3,855 | 0 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 5,010 | 10,019 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 27,402 | 27,402 | - | - | Common Stock Option | |
| Laurent Humeau | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 22,098 | 22,098 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.98 per share. | 26 Feb 2025 | 9,088 | 46,550 (0%) | 0% | 2.0 | 17,994 | Common Stock |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 18,632 | 55,638 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.98 per share. | 26 Feb 2025 | 2,493 | 37,006 (0%) | 0% | 2.0 | 4,936 | Common Stock |
| Jacqueline E. Shea | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 85,201 | 85,201 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 105,649 | 105,649 | - | - | Common Stock Option | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 18,632 | 37,263 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 5,852 | 0 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 5,852 | 39,499 (0%) | 0% | - | Common Stock | |
| Michael John Sumner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 5,010 | 10,019 | - | - | Restricted Stock Unit | |
| Michael John Sumner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 5,010 | 13,229 (0%) | 0% | - | Common Stock | |
| Michael John Sumner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 42,900 | 42,900 | - | - | Common Stock Option | |
| Michael John Sumner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2025 | 34,650 | 34,650 | - | - | Restricted Stock Unit | |
| John Michael Sumner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2024 | 4,292 | 4,292 | - | - | Restricted Stock Unit | |
| Michael Sumner John | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2024 | 5,708 | 5,708 | - | - | Common Stock Option | |
| Michael John Sumner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2024 | 2,917 | 8,219 (0%) | 0% | - | Common Stock | |
| Michael John Sumner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2024 | 2,917 | 2,916 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,917 | 2,917 | - | - | Common Stock Options | |
| Lota S. Zoth | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,167 | 2,167 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,917 | 2,917 | - | - | Common Stock Options | |
| Simon X. Benito | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,167 | 2,167 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,167 | 2,167 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,917 | 2,917 | - | - | Common Stock Options | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,167 | 2,167 | - | - | Restricted Stock Unit | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,917 | 2,917 | - | - | Common Stock Options | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,917 | 2,917 | - | - | Common Stock Options | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,167 | 2,167 | - | - | Restricted Stock Unit | |
| Roger D. Dansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,167 | 2,167 | - | - | Restricted Stock Unit | |
| Roger D. Dansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,917 | 2,917 | - | - | Common Stock Options | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,917 | 2,917 | - | - | Common Stock Options | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 May 2024 | 2,167 | 2,167 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 0 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 6,559 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 4,771 | 26,929 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 13.07 per share. | 15 May 2024 | 2,562 | 24,367 (0%) | 0% | 13.1 | 33,485 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 4,771 | 9,542 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 10,024 (0%) | 0% | - | Common Stock | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 0 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 0 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 8,345 (0%) | 0% | - | Common Stock | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 7,042 (0%) | 0% | - | Common Stock | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 82,509 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 0 | - | - | Restricted Stock Unit | |
| Roger D. Dansey | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 6,749 (0%) | 0% | - | Common Stock | |
| Roger D. Dansey | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 0 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 4,771 | 9,542 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 13.07 per share. | 15 May 2024 | 1,703 | 24,337 (0%) | 0% | 13.1 | 22,258 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 4,771 | 26,040 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 17,745 | 35,488 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 17,745 | 41,365 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 13.07 per share. | 15 May 2024 | 7,718 | 33,647 (0%) | 0% | 13.1 | 100,874 | Common Stock |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 0 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,166 | 7,710 (0%) | 0% | - | Common Stock | |
| Michael John Sumner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,386 | 5,302 (0%) | 0% | - | Common Stock | |
| Michael John Sumner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2024 | 2,386 | 4,770 | - | - | Restricted Stock Unit | |
| Roger D. Dansey | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2024 | 1,000 | 4,583 (0%) | 0% | - | Common Stock | |
| Roger D. Dansey | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2024 | 1,000 | 0 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.65 per share. | 10 May 2024 | 2,392 | 23,620 (0%) | 0% | 10.7 | 25,475 | Common Stock |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2024 | 5,500 | 26,012 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2024 | 5,500 | 5,500 | - | - | Restricted Stock Unit | |
| John Sumner Michael | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2024 | 15,029 | 15,029 | - | - | Restricted Stock Unit | |
| John Michael Sumner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Feb 2024 | 18,750 | 18,750 | - | - | Common Stock Option | |
| D. Kies Peter | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 18,750 | 18,750 | - | - | Common Stock Option | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 3,856 | 22,850 (0%) | 0% | - | Common Stock | |
| B. David Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 972 | 0 | - | - | Restricted Stock Unit | |
| E. Shea Jacqueline | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.16 per share. | 26 Feb 2024 | 872 | 17,515 (0%) | 0% | 8.2 | 7,116 | Common Stock |
| Shea E. Jacqueline | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 5,853 | 23,368 (0%) | 0% | - | Common Stock | |
| Jacqueline Shea E. | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 1,878 | 0 | - | - | Restricted Stock Unit | |
| David Weiner B. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 972 | 79,371 (0%) | 0% | - | Common Stock | |
| Weiner B. David | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 972 | 80,343 (0%) | 0% | - | Common Stock | |
| Shea Jacqueline E. | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.16 per share. | 26 Feb 2024 | 2,856 | 20,512 (0%) | 0% | 8.2 | 23,305 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 1,878 | 0 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 3,856 | 3,855 | - | - | Restricted Stock Unit | |
| Humeau Laurent | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.16 per share. | 26 Feb 2024 | 1,581 | 21,269 (0%) | 0% | 8.2 | 12,901 | Common Stock |
| D. Peter Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.16 per share. | 26 Feb 2024 | 1,108 | 20,519 (0%) | 0% | 8.2 | 9,041 | Common Stock |
| B. Weiner David | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 972 | 972 | - | - | Restricted Stock Unit | |
| Kies D. Peter | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 1,878 | 21,627 (0%) | 0% | - | Common Stock | |
| D. Kies Peter | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 3,997 | 24,516 (0%) | 0% | - | Common Stock | |
| E. Jacqueline Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 5,853 | 5,852 | - | - | Restricted Stock Unit | |
| Shea Jacqueline E. | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 55,895 | 55,895 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 3,997 | 3,997 | - | - | Restricted Stock Unit | |
| Kies D. Peter | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 15,029 | 15,029 | - | - | Restricted Stock Unit | |
| Humeau Laurent | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 1,878 | 19,764 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 18,750 | 18,750 | - | - | Common Stock Option | |
| E. Jacqueline Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 1,878 | 18,387 (0%) | 0% | - | Common Stock | |
| Kies D. Peter | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.16 per share. | 26 Feb 2024 | 2,358 | 22,158 (0%) | 0% | 8.2 | 19,241 | Common Stock |
| David Weiner B. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 972 | 1,944 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 972 | 78,399 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 15,029 | 15,029 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2024 | 1,878 | 0 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.16 per share. | 26 Feb 2024 | 770 | 18,994 (0%) | 0% | 8.2 | 6,283 | Common Stock |
| E. Jacqueline Shea | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 69,733 | 69,733 | - | - | Common Stock Option | |
| Michael John Sumner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2023 | 35,000 | 70,000 | - | - | Restricted Stock Unit | |
| Michael John Sumner | Chief Medical Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2023 | 35,000 | 35,000 (0%) | 0% | - | Common Stock | |
| Lota S. Zoth | Director | Sale of securities on an exchange or to another person at price $ 0.56 per share. | 05 Jun 2023 | 5,700 | 52,716 (0%) | 0% | 0.6 | 3,192 | Common Stock |
| Lota S. Zoth | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 26,000 | 26,000 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 35,000 | 35,000 | - | - | Common Stock Options | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 0 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 58,416 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 171,756 | 171,756 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 0 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 94,305 (0%) | 0% | - | Common Stock | |
| Simon X. Benito | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 26,000 | 26,000 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 35,000 | 35,000 | - | - | Common Stock Options | |
| Wendy L. Yarno | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 26,000 | 26,000 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 35,000 | 35,000 | - | - | Common Stock Options | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 0 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 74,153 (0%) | 0% | - | Common Stock | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 26,000 | 26,000 | - | - | Restricted Stock Unit | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 35,000 | 35,000 | - | - | Common Stock Options | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 0 | - | - | Restricted Stock Unit | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 58,521 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 26,000 | 26,000 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 35,000 | 35,000 | - | - | Common Stock Options | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 929,124 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 171,756 | 171,756 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 638,800 | 638,800 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 0 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 19,000 | 66,534 (0%) | 0% | - | Common Stock | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 26,000 | 26,000 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 35,000 | 35,000 | - | - | Common Stock Options | |
| Michael John Sumner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2023 | 85,878 | 85,878 | - | - | Restricted Stock Unit | |
| Roger D. Dansey | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2023 | 19,000 | 43,000 (0%) | 0% | - | Common Stock | |
| Roger D. Dansey | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2023 | 19,000 | 0 | - | - | Restricted Stock Unit | |
| Roger D. Dansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2023 | 35,000 | 35,000 | - | - | Common Stock Options | |
| Roger D. Dansey | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2023 | 12,000 | 12,000 | - | - | Restricted Stock Unit | |
| Roger D. Dansey | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2023 | 12,000 | 24,000 (0%) | 0% | - | Common Stock | |
| Roger D. Dansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2023 | 26,000 | 26,000 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2023 | 66,000 | 226,817 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.81 per share. | 10 May 2023 | 28,704 | 198,113 (0%) | 0% | 0.8 | 23,250 | Common Stock |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 May 2023 | 66,000 | 132,000 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2023 | 59,737 | 268,409 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.13 per share. | 11 Mar 2023 | 31,410 | 236,999 (0%) | 0% | 1.1 | 35,493 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2023 | 59,737 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2023 | 11,666 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 1.15 per share. | 11 Mar 2023 | 5,833 | 910,124 (0%) | 0% | 1.2 | 6,708 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2023 | 11,666 | 915,957 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2023 | 59,737 | 0 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.13 per share. | 11 Mar 2023 | 20,658 | 214,637 (0%) | 0% | 1.1 | 23,344 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2023 | 59,737 | 235,295 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2023 | 59,737 | 0 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.13 per share. | 11 Mar 2023 | 25,980 | 160,817 (0%) | 0% | 1.1 | 29,357 | Common Stock |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2023 | 59,737 | 186,797 (0%) | 0% | - | Common Stock | |
| Michael John Sumner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2023 | 112,500 | 112,500 | - | - | Common Stock Option | |
| Peter D. Kies | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2023 | 225,000 | 225,000 | - | - | Common Stock Option | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 47,967 | 95,933 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 22,544 | 22,544 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.28 per share. | 26 Feb 2023 | 28,195 | 208,672 (0%) | 0% | 1.3 | 36,090 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 47,967 | 236,867 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.28 per share. | 26 Feb 2023 | 12,928 | 188,900 (0%) | 0% | 1.3 | 16,548 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 22,544 | 201,828 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2023 | 35,000 | 35,000 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2023 | 60,000 | 60,000 | - | - | Common Stock Option | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 11,667 | 23,333 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 11,667 | 11,666 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 1.28 per share. | 26 Feb 2023 | 11,668 | 904,291 (0%) | 0% | 1.3 | 14,935 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 11,667 | 915,959 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 11,667 | 904,292 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2023 | 225,000 | 225,000 | - | - | Common Stock Option | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 46,267 | 92,533 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 22,544 | 22,544 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.28 per share. | 26 Feb 2023 | 18,868 | 175,558 (0%) | 0% | 1.3 | 24,151 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 46,267 | 194,426 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.28 per share. | 26 Feb 2023 | 9,069 | 148,159 (0%) | 0% | 1.3 | 11,608 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 22,544 | 157,228 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 22,544 | 99,099 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2023 | 836,800 | 836,800 | - | - | Common Stock Option | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 70,234 | 140,466 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 22,544 | 22,544 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.28 per share. | 26 Feb 2023 | 32,485 | 127,060 (0%) | 0% | 1.3 | 41,581 | Common Stock |
| Jacqueline E. Shea | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2023 | 70,234 | 159,545 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 1.28 per share. | 26 Feb 2023 | 9,788 | 89,311 (0%) | 0% | 1.3 | 12,529 | Common Stock |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2023 | 4,273 | 0 | - | - | Restricted Stock Unit | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2023 | 4,273 | 39,521 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Aug 2022 | 11,875 | 11,875 | - | - | Common Stock Option | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 2.66 per share. | 11 Aug 2022 | 11,875 | 892,625 (0%) | 0% | 2.7 | 31,588 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.16 per share. | 11 Aug 2022 | 11,875 | 904,500 (0%) | 0% | 2.2 | 25,650 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.20 per share. | 20 Jul 2022 | 2,000 | 77,305 (0%) | 0% | 2.2 | 4,400 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Jul 2022 | 2,000 | 4,000 | - | - | Common Stock Options | |
| Simon X. Benito | Director | Sale of securities on an exchange or to another person at price $ 2.25 per share. | 20 Jul 2022 | 2,000 | 75,305 (0%) | 0% | 2.3 | 4,500 | Common Stock |
| Michael John Sumner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2022 | 105,000 | 105,000 | - | - | Restricted Stock Unit | |
| Michael John Sumner | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2022 | 160,000 | 160,000 | - | - | Common Stock Options | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 43,016 (0%) | 0% | - | Common Stock | |
| Lota S. Zoth | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 28,000 | 28,000 | - | - | Common Stock Options | |
| Lota S. Zoth | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 19,000 | 19,000 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 0 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Sale of securities on an exchange or to another person at price $ 1.98 per share. | 13 May 2022 | 3,600 | 39,416 (0%) | 0% | 2.0 | 7,128 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 0 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 19,000 | 19,000 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 28,000 | 28,000 | - | - | Common Stock Options | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 75,305 (0%) | 0% | - | Common Stock | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 55,153 (0%) | 0% | - | Common Stock | |
| Wendy L. Yarno | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 19,000 | 19,000 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 28,000 | 28,000 | - | - | Common Stock Options | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 0 | - | - | Restricted Stock Unit | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 35,248 (0%) | 0% | - | Common Stock | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 28,000 | 28,000 | - | - | Common Stock Options | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 19,000 | 19,000 | - | - | Restricted Stock Unit | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 1.95 per share. | 13 May 2022 | 9,000 | 892,625 (0%) | 0% | 2.0 | 17,550 | Common Stock |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 19,000 | 19,000 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 28,000 | 28,000 | - | - | Common Stock Options | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 901,625 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 0 | - | - | Restricted Stock Unit | |
| Roger D. Dansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 19,000 | 19,000 | - | - | Restricted Stock Unit | |
| Roger D. Dansey | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 12,000 | 12,000 (0%) | 0% | - | Common Stock | |
| Roger D. Dansey | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 12,000 | 24,000 | - | - | Restricted Stock Unit | |
| Roger D. Dansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 28,000 | 28,000 | - | - | Common Stock Options | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 47,534 (0%) | 0% | - | Common Stock | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2022 | 18,000 | 0 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 19,000 | 19,000 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2022 | 28,000 | 28,000 | - | - | Common Stock Options | |
| Jacqueline E. Shea | Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2022 | 198,000 | 198,000 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2022 | 309,400 | 309,400 | - | - | Common Stock Option | |
| Jacqueline E. Shea | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.63 per share. | 25 Mar 2022 | 7,247 | 76,555 (0%) | 0% | 3.6 | 26,307 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Mar 2022 | 16,666 | 0 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Mar 2022 | 16,666 | 83,802 (0%) | 0% | - | Common Stock | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2022 | 4,273 | 0 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2022 | 4,273 | 29,534 (0%) | 0% | - | Common Stock | |
| Simon X. Benito | Director | Sale of securities on an exchange or to another person at price $ 3.16 per share. | 16 Mar 2022 | 2,000 | 57,305 (0%) | 0% | 3.2 | 6,320 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Mar 2022 | 2,000 | 6,000 | - | - | Common Stock Options | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.20 per share. | 16 Mar 2022 | 2,000 | 59,305 (0%) | 0% | 2.2 | 4,400 | Common Stock |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.22 per share. | 11 Mar 2022 | 31,410 | 179,284 (0%) | 0% | 3.2 | 101,140 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 59,737 | 210,694 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 59,737 | 59,737 | - | - | Restricted Stock Unit | |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 139,387 | 1,462,325 (1%) | 0% | - | Common Stock | |
| Kim Joseph Jong | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.22 per share. | 11 Mar 2022 | 39,698 | 1,422,627 (1%) | 0% | 3.2 | 127,828 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 139,387 | 139,386 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 3.20 per share. | 11 Mar 2022 | 4,083 | 883,625 (0%) | 0% | 3.2 | 13,066 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 11,667 | 11,666 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 11,667 | 887,708 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 59,737 | 155,342 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 59,737 | 59,737 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.22 per share. | 11 Mar 2022 | 20,658 | 134,684 (0%) | 0% | 3.2 | 66,519 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 59,737 | 155,342 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 59,737 | 59,737 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.22 per share. | 11 Mar 2022 | 20,658 | 134,684 (0%) | 0% | 3.2 | 66,519 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 59,737 | 93,110 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2022 | 59,737 | 59,737 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.22 per share. | 11 Mar 2022 | 25,974 | 67,136 (0%) | 0% | 3.2 | 83,636 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2022 | 21,466 | 162,244 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.26 per share. | 08 Mar 2022 | 11,287 | 150,957 (0%) | 0% | 3.3 | 36,796 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2022 | 21,466 | 0 | - | - | Restricted Stock Unit | |
| Kim Joseph Jong | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.26 per share. | 08 Mar 2022 | 18,142 | 1,322,938 (1%) | 0% | 3.3 | 59,143 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2022 | 63,700 | 1,341,080 (1%) | 0% | - | Common Stock | |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2022 | 63,700 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 3.33 per share. | 08 Mar 2022 | 4,083 | 876,041 (0%) | 0% | 3.3 | 13,596 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2022 | 11,666 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2022 | 11,666 | 880,124 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2022 | 19,900 | 0 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Mar 2022 | 19,900 | 102,487 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.26 per share. | 08 Mar 2022 | 6,882 | 95,605 (0%) | 0% | 3.3 | 22,435 | Common Stock |
| Peter D. Kies | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2022 | 143,900 | 143,900 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2022 | 192,800 | 192,800 | - | - | Common Stock Option | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2022 | 22,545 | 45,088 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.22 per share. | 26 Feb 2022 | 12,555 | 140,778 (0%) | 0% | 3.2 | 40,427 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2022 | 22,545 | 153,333 (0%) | 0% | - | Common Stock | |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2022 | 68,767 | 1,297,425 (1%) | 0% | - | Common Stock | |
| Kim Joseph Jong | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2022 | 468,500 | 468,500 | - | - | Restricted Stock Unit | |
| Kim Joseph Jong | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2022 | 627,700 | 627,700 | - | - | Common Stock Option | |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2022 | 68,767 | 137,533 | - | - | Restricted Stock Unit | |
| Kim Joseph Jong | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.22 per share. | 26 Feb 2022 | 20,045 | 1,277,380 (1%) | 0% | 3.2 | 64,545 | Common Stock |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2022 | 35,000 | 35,000 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2022 | 60,000 | 60,000 | - | - | Common Stock Option | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2022 | 11,667 | 23,333 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2022 | 11,667 | 868,458 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2022 | 22,545 | 91,132 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.22 per share. | 26 Feb 2022 | 8,545 | 82,587 (0%) | 0% | 3.2 | 27,515 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2022 | 138,800 | 138,800 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2022 | 186,000 | 186,000 | - | - | Common Stock Option | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2022 | 22,545 | 45,088 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 3.22 per share. | 26 Feb 2022 | 10,764 | 33,373 (0%) | 0% | 3.2 | 34,660 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2022 | 210,700 | 210,700 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2022 | 282,300 | 282,300 | - | - | Common Stock Option | |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2022 | 22,545 | 45,088 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2022 | 22,545 | 44,137 (0%) | 0% | - | Common Stock | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.20 per share. | 19 Jan 2022 | 2,000 | 59,305 (0%) | 0% | 2.2 | 4,400 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Jan 2022 | 2,000 | 8,000 | - | - | Common Stock Options | |
| Simon X. Benito | Director | Sale of securities on an exchange or to another person at price $ 4.27 per share. | 19 Jan 2022 | 2,000 | 57,305 (0%) | 0% | 4.3 | 8,540 | Common Stock |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2022 | 4,274 | 17,248 (0%) | 0% | - | Common Stock | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2022 | 4,274 | 4,273 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jan 2022 | 4,090 | 25,977 (0%) | 0% | - | Common Stock | |
| Lota S. Zoth | Director | Sale of securities on an exchange or to another person at price $ 5.01 per share. | 03 Jan 2022 | 961 | 25,016 (0%) | 0% | 5.0 | 4,815 | Common Stock |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jan 2022 | 4,090 | 0 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.15 per share. | 09 Aug 2021 | 10,317 | 68,587 (0%) | 0% | 9.2 | 94,401 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Jun 2021 | 13,750 | 20,000 | - | - | Common Stock Option | |
| Peter D. Kies | CFO | Sale of securities on an exchange or to another person at price $ 10.01 per share. | 09 Jun 2021 | 33,750 | 130,788 (0%) | 0% | 10.0 | 337,838 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.16 per share. | 09 Jun 2021 | 13,750 | 164,538 (0%) | 0% | 2.2 | 29,700 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.07 per share. | 09 Jun 2021 | 10,318 | 78,904 (0%) | 0% | 9.1 | 93,584 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 10.01 per share. | 09 Jun 2021 | 38,535 | 21,592 (0%) | 0% | 10.0 | 385,735 | Common Stock |
| Peter D. Kies | CFO | Sale of securities on an exchange or to another person at price $ 8.03 per share. | 03 Jun 2021 | 10,000 | 150,788 (0%) | 0% | 8.0 | 80,300 | Common Stock |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 0 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 18,000 | 18,000 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 27,000 | 27,000 | - | - | Common Stock Options | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 23,932 (0%) | 0% | - | Common Stock | |
| Lota S. Zoth | Director | Sale of securities on an exchange or to another person at price $ 6.62 per share. | 13 May 2021 | 2,045 | 21,887 (0%) | 0% | 6.6 | 13,538 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 0 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 18,000 | 18,000 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 27,000 | 27,000 | - | - | Common Stock Options | |
| Simon X. Benito | Director | Sale of securities on an exchange or to another person at price $ 6.62 per share. | 13 May 2021 | 3,045 | 57,305 (0%) | 0% | 6.6 | 20,158 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 60,350 (0%) | 0% | - | Common Stock | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 0 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 27,000 | 27,000 | - | - | Common Stock Options | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 37,153 (0%) | 0% | - | Common Stock | |
| Wendy L. Yarno | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 18,000 | 18,000 | - | - | Restricted Stock Unit | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 27,000 | 27,000 | - | - | Common Stock Options | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 18,000 | 18,000 | - | - | Restricted Stock Unit | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 0 | - | - | Restricted Stock Unit | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 12,974 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 27,000 | 27,000 | - | - | Common Stock Options | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 18,000 | 18,000 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 6.62 per share. | 13 May 2021 | 3,045 | 856,791 (0%) | 0% | 6.6 | 20,158 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 859,836 (0%) | 0% | - | Common Stock | |
| Roger D. Dansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 54,000 | 54,000 | - | - | Common Stock Options | |
| Roger D. Dansey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 36,000 | 36,000 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 25,261 (0%) | 0% | - | Common Stock | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2021 | 8,700 | 0 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 18,000 | 18,000 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2021 | 27,000 | 27,000 | - | - | Common Stock Options | |
| Peter D. Kies | CFO | Sale of securities on an exchange or to another person at price $ 8.52 per share. | 21 Apr 2021 | 10,000 | 160,788 (0%) | 0% | 8.5 | 85,200 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Apr 2021 | 22,500 | 0 | - | - | Common Stock Options | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 8.54 per share. | 21 Apr 2021 | 4,083 | 851,136 (0%) | 0% | 8.5 | 34,869 | Common Stock |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 8.57 per share. | 21 Apr 2021 | 22,500 | 855,219 (0%) | 0% | 8.6 | 192,825 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.40 per share. | 21 Apr 2021 | 22,500 | 877,719 (0%) | 0% | 2.4 | 54,000 | Common Stock |
| Simon X. Benito | Director | Sale of securities on an exchange or to another person at price $ 8.75 per share. | 16 Apr 2021 | 2,000 | 51,650 (0%) | 0% | 8.8 | 17,500 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Apr 2021 | 2,000 | 0 | - | - | Common Stock Options | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.56 per share. | 16 Apr 2021 | 2,000 | 53,650 (0%) | 0% | 3.6 | 7,120 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 9.06 per share. | 25 Mar 2021 | 7,247 | 64,837 (0%) | 0% | 9.1 | 65,658 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Mar 2021 | 16,667 | 16,666 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 8.97 per share. | 25 Mar 2021 | 4,710 | 60,127 (0%) | 0% | 9.0 | 42,249 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Mar 2021 | 16,667 | 72,084 (0%) | 0% | - | Common Stock | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2021 | 4,274 | 4,273 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2021 | 4,274 | 16,561 (0%) | 0% | - | Common Stock | |
| Simon X. Benito | Director | Sale of securities on an exchange or to another person at price $ 10.41 per share. | 16 Mar 2021 | 2,000 | 51,650 (0%) | 0% | 10.4 | 20,820 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Mar 2021 | 2,000 | 2,000 | - | - | Common Stock Options | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.56 per share. | 16 Mar 2021 | 2,000 | 53,650 (0%) | 0% | 3.6 | 7,120 | Common Stock |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.57 per share. | 11 Mar 2021 | 31,410 | 170,788 (0%) | 0% | 10.6 | 332,004 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 59,737 | 119,474 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 59,737 | 202,198 (0%) | 0% | - | Common Stock | |
| Kim Joseph Jong | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.57 per share. | 11 Mar 2021 | 74,545 | 1,228,658 (1%) | 0% | 10.6 | 787,941 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 139,387 | 1,303,203 (1%) | 0% | - | Common Stock | |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 139,387 | 278,773 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 11,667 | 23,333 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 11,667 | 855,219 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.57 per share. | 11 Mar 2021 | 25,967 | 89,222 (0%) | 0% | 10.6 | 274,471 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 59,737 | 119,474 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 59,737 | 115,189 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 10.57 per share. | 11 Mar 2021 | 25,974 | 72,298 (0%) | 0% | 10.6 | 274,545 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 59,737 | 98,272 (0%) | 0% | - | Common Stock | |
| Jacqueline E. Shea | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 10.06 per share. | 11 Mar 2021 | 16,881 | 55,417 (0%) | 0% | 10.1 | 169,823 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Mar 2021 | 59,737 | 119,474 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 27,566 | 146,856 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 9.19 per share. | 05 Mar 2021 | 14,574 | 132,282 (0%) | 0% | 9.2 | 133,935 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 21,467 | 153,749 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.91 per share. | 05 Mar 2021 | 11,288 | 142,461 (0%) | 0% | 8.9 | 100,576 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 27,566 | 0 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 21,467 | 21,466 | - | - | Restricted Stock Unit | |
| Kim Joseph Jong | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.91 per share. | 05 Mar 2021 | 34,067 | 1,163,816 (1%) | 0% | 8.9 | 303,537 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 63,700 | 1,197,883 (1%) | 0% | - | Common Stock | |
| Kim Joseph Jong | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 9.19 per share. | 05 Mar 2021 | 64,230 | 1,134,183 (1%) | 0% | 9.2 | 590,274 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 120,100 | 1,198,413 (1%) | 0% | - | Common Stock | |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 63,700 | 63,700 | - | - | Restricted Stock Unit | |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 120,100 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 11,666 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 11,667 | 11,666 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 9.60 per share. | 05 Mar 2021 | 3,500 | 843,552 (0%) | 0% | 9.6 | 33,601 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 11,667 | 847,052 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 9.18 per share. | 05 Mar 2021 | 3,500 | 835,385 (0%) | 0% | 9.2 | 32,135 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 11,666 | 838,885 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 27,566 | 52,066 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 9.19 per share. | 05 Mar 2021 | 9,632 | 42,434 (0%) | 0% | 9.2 | 88,518 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 19,900 | 62,334 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 8.91 per share. | 05 Mar 2021 | 6,882 | 55,452 (0%) | 0% | 8.9 | 61,319 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 27,566 | 0 | - | - | Restricted Stock Unit | |
| Laurent Humeau | Chief Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2021 | 19,900 | 19,900 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2021 | 67,633 | 67,633 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2021 | 104,833 | 104,833 | - | - | Common Stock Option | |
| Kim Joseph Jong | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2021 | 206,300 | 206,300 | - | - | Restricted Stock Unit | |
| Kim Joseph Jong | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2021 | 319,800 | 319,800 | - | - | Common Stock Option | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2021 | 35,000 | 35,000 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2021 | 60,000 | 60,000 | - | - | Common Stock Option | |
| Laurent Humeau | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2021 | 104,833 | 104,833 | - | - | Common Stock Option | |
| Laurent Humeau | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2021 | 67,633 | 67,633 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2021 | 67,633 | 67,633 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2021 | 104,833 | 104,833 | - | - | Common Stock Option | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.56 per share. | 16 Feb 2021 | 2,000 | 53,650 (0%) | 0% | 3.6 | 7,120 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2021 | 2,000 | 4,000 | - | - | Common Stock Options | |
| Simon X. Benito | Director | Sale of securities on an exchange or to another person at price $ 14.68 per share. | 16 Feb 2021 | 2,000 | 51,650 (0%) | 0% | 14.7 | 29,360 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 14.24 per share. | 01 Feb 2021 | 62,500 | 1,078,313 (1%) | 0% | 14.2 | 890,000 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 15.00 per share. | 01 Feb 2021 | 100,000 | 1,078,313 (1%) | 0% | 15 | 1,500,000 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.56 per share. | 01 Feb 2021 | 62,500 | 1,140,813 (1%) | 0% | 4.6 | 285,000 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2021 | 62,500 | 0 | - | - | Common Stock Option | |
| Jacqueline E. Shea | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 15.06 per share. | 01 Feb 2021 | 22,376 | 44,495 (0%) | 0% | 15.1 | 336,983 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Feb 2021 | 22,376 | 100,000 | - | - | Common Stock Option | |
| Jacqueline E. Shea | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 15.00 per share. | 01 Feb 2021 | 5,960 | 38,535 (0%) | 0% | 15 | 89,400 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.62 per share. | 01 Feb 2021 | 22,376 | 66,871 (0%) | 0% | 3.6 | 81,001 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 12.01 per share. | 27 Jan 2021 | 22,376 | 11,920 (0%) | 0% | 12.0 | 268,736 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2021 | 55,248 | 122,376 | - | - | Common Stock Option | |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jan 2021 | 22,376 | 177,624 | - | - | Common Stock Option | |
| Jacqueline E. Shea | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 12.04 per share. | 27 Jan 2021 | 16,713 | 44,495 (0%) | 0% | 12.0 | 201,225 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.62 per share. | 27 Jan 2021 | 55,248 | 61,208 (0%) | 0% | 3.6 | 199,998 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 12.04 per share. | 27 Jan 2021 | 5,960 | 5,960 (0%) | 0% | 12.0 | 71,758 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.62 per share. | 27 Jan 2021 | 22,376 | 34,296 (0%) | 0% | 3.6 | 81,001 | Common Stock |
| Peter D. Kies | CFO | Sale of securities on an exchange or to another person at price $ 10.02 per share. | 15 Jan 2021 | 30,000 | 119,290 (0%) | 0% | 10.0 | 300,558 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2021 | 30,000 | 0 | - | - | Common Stock Option | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.56 per share. | 15 Jan 2021 | 30,000 | 149,290 (0%) | 0% | 4.6 | 136,800 | Common Stock |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2021 | 4,274 | 8,547 | - | - | Restricted Stock Unit | |
| Jay P. Shepard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2021 | 4,274 | 4,274 (0%) | 0% | - | Common Stock | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.56 per share. | 04 Jan 2021 | 2,750 | 54,400 (0%) | 0% | 3.6 | 9,790 | Common Stock |
| Simon X. Benito | Director | Sale of securities on an exchange or to another person at price $ 9.00 per share. | 04 Jan 2021 | 2,750 | 51,650 (0%) | 0% | 9 | 24,750 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jan 2021 | 2,750 | 6,000 | - | - | Common Stock Options | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jan 2021 | 4,090 | 16,193 (0%) | 0% | - | Common Stock | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Jan 2021 | 4,090 | 4,090 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Sale of securities on an exchange or to another person at price $ 9.48 per share. | 03 Jan 2021 | 961 | 15,232 (0%) | 0% | 9.5 | 9,110 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 29 Dec 2020 | 10,000 | 1,178,313 (1%) | 0% | 0 | Common Stock | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.16 per share. | 15 Dec 2020 | 11,250 | 139,290 (0%) | 0% | 2.2 | 24,300 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2020 | 11,250 | 33,750 | - | - | Common Stock Option | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2020 | 8,750 | 0 | - | - | Common Stock Option | |
| Peter D. Kies | CFO | Sale of securities on an exchange or to another person at price $ 10.69 per share. | 15 Dec 2020 | 20,000 | 119,290 (0%) | 0% | 10.7 | 213,706 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.40 per share. | 15 Dec 2020 | 8,750 | 128,040 (0%) | 0% | 2.4 | 21,000 | Common Stock |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 10.71 per share. | 15 Dec 2020 | 17,500 | 827,219 (0%) | 0% | 10.7 | 187,352 | Common Stock |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2020 | 17,500 | 0 | - | - | Common Stock Option | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.56 per share. | 15 Dec 2020 | 17,500 | 844,719 (0%) | 0% | 4.6 | 79,800 | Common Stock |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Dec 2020 | 4,090 | 0 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Dec 2020 | 4,090 | 28,453 (0%) | 0% | - | Common Stock | |
| Laurent Humeau | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 9.75 per share. | 10 Nov 2020 | 19,466 | 24,500 (0%) | 0% | 9.8 | 189,794 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.06 per share. | 10 Aug 2020 | 19,467 | 43,966 (0%) | 0% | 19.1 | 371,004 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Sale of securities on an exchange or to another person at price $ 21.13 per share. | 30 Jul 2020 | 100,000 | 1,188,313 (1%) | 0% | 21.1 | 2,113,450 | Common Stock |
| Peter D. Kies | CFO | Sale of securities on an exchange or to another person at price $ 24.95 per share. | 15 Jul 2020 | 35,000 | 119,290 (0%) | 0% | 24.9 | 873,208 | Common Stock |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jul 2020 | 35,000 | 0 | - | - | Common Stock Option | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.40 per share. | 15 Jul 2020 | 35,000 | 154,290 (0%) | 0% | 2.4 | 84,000 | Common Stock |
| Peter D. Kies | CFO | Sale of securities on an exchange or to another person at price $ 26.50 per share. | 30 Jun 2020 | 35,000 | 119,290 (0%) | 0% | 26.5 | 927,500 | Common Stock |
| Laurent Humeau | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 14.70 per share. | 22 Jun 2020 | 19,467 | 63,433 (0%) | 0% | 14.7 | 286,165 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.60 per share. | 20 May 2020 | 8,750 | 60,400 (0%) | 0% | 4.6 | 40,250 | Common Stock |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 May 2020 | 8,750 | 0 | - | - | Common Stock Option | |
| Simon X. Benito | Director | Sale of securities on an exchange or to another person at price $ 15.95 per share. | 20 May 2020 | 8,750 | 51,650 (0%) | 0% | 16.0 | 139,594 | Common Stock |
| Lota S. Zoth | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 13,300 | 13,300 | - | - | Common Stock Options | |
| Lota S. Zoth | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 8,700 | 8,700 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 8,700 | 8,700 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 13,300 | 13,300 | - | - | Common Stock Options | |
| Wendy L. Yarno | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 8,700 | 8,700 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 13,300 | 13,300 | - | - | Common Stock Options | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 13,300 | 13,300 | - | - | Common Stock Options | |
| Jay P. Shepard | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 8,700 | 8,700 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 13,300 | 13,300 | - | - | Common Stock Options | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 8,700 | 8,700 | - | - | Restricted Stock Unit | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 13,300 | 13,300 | - | - | Common Stock Options | |
| Ann C. Miller | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2020 | 8,700 | 8,700 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Sale of securities on an exchange or to another person at price $ 11.84 per share. | 11 May 2020 | 2,404 | 827,219 (0%) | 0% | 11.8 | 28,463 | Common Stock |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 0 | - | - | Restricted Stock Unit | |
| Lota S. Zoth | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 12,103 (0%) | 0% | - | Common Stock | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 0 | - | - | Restricted Stock Unit | |
| Simon X. Benito | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 51,650 (0%) | 0% | - | Common Stock | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 0 | - | - | Restricted Stock Unit | |
| Wendy L. Yarno | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 24,363 (0%) | 0% | - | Common Stock | |
| Angel Cabrera | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 0 | - | - | Restricted Stock Unit | |
| Angel Cabrera | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 75,602 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 829,623 (0%) | 0% | - | Common Stock | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 12,287 (0%) | 0% | - | Common Stock | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 May 2020 | 8,013 | 0 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 6.68 per share. | 25 Mar 2020 | 4,747 | 11,920 (0%) | 0% | 6.7 | 31,710 | Common Stock |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Mar 2020 | 16,667 | 33,333 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Mar 2020 | 16,667 | 16,667 (0%) | 0% | - | Common Stock | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2020 | 4,274 | 4,274 (0%) | 0% | - | Common Stock | |
| Ann C. Miller | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Mar 2020 | 4,274 | 8,547 | - | - | Restricted Stock Unit | |
| Jacqueline E. Shea | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Mar 2020 | 179,211 | 179,211 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2020 | 20,433 | 161,356 (0%) | 0% | - | Common Stock | |
| Peter D. Kies | CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2020 | 179,211 | 179,211 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2020 | 20,433 | 0 | - | - | Restricted Stock Unit | |
| Peter D. Kies | CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.70 per share. | 10 Mar 2020 | 7,066 | 154,290 (0%) | 0% | 5.7 | 40,276 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.70 per share. | 10 Mar 2020 | 36,826 | 1,288,313 (1%) | 0% | 5.7 | 209,908 | Common Stock |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2020 | 105,700 | 1,325,139 (1%) | 0% | - | Common Stock | |
| Kim Joseph Jong | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2020 | 418,160 | 418,160 | - | - | Restricted Stock Unit | |
| Kim Joseph Jong | Director, Chief Executive Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2020 | 105,700 | 0 | - | - | Restricted Stock Unit | |
| David B. Weiner | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Mar 2020 | 11,666 | 828,610 (0%) | 0% | - | Common Stock | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2020 | 60,000 | 60,000 | - | - | Common Stock Option | |
| David B. Weiner | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2020 | 35,000 | 35,000 | - | - | Restricted Stock Unit |